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SERVICES

Consulting built around the questions that matter.

Flexible scientific support for teams developing, manufacturing, characterizing or troubleshooting lentiviral vectors.

01

UPSTREAM

Vector Production Development

Development and troubleshooting of lentiviral vector production workflows, including HEK293-based systems, transient transfection strategy, process variables, harvest timing and productivity/function relationships.

  • Production strategy and process mapping
  • Transfection and culture parameter assessment
  • Functional titer improvement strategy
  • Scale-up risk assessment
02

DOWNSTREAM

Purification & Process Development

Practical evaluation of recovery, concentration, purification and process robustness from harvest through final material.

  • Clarification and concentration strategy
  • Membrane and chromatography considerations
  • Recovery and impurity tradeoffs
  • Process troubleshooting and optimization
03

ANALYTICS

Characterization & Functional Quality

Analytical strategies that distinguish particle quantity from biological performance and help explain why apparently similar vector preparations can behave differently.

  • Particle and physical characterization
  • p24, nucleic-acid and functional titer strategy
  • Transduction and potency-related readouts
  • Orthogonal analytical frameworks
04

DEVELOPMENT

Scale-up, Comparability & Technical Strategy

Translate laboratory learning into development decisions for larger-scale manufacturing and future process stages.

  • Critical parameter and risk mapping
  • Comparability strategy
  • Development plans and experiment prioritization
  • Technical reports and decision support

NEXT STEPS

Ready to tackle your vector challenges?

Get in touch to explore how LentiWorks can provide targeted consulting for your development pipeline.

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